       
|
|
|
Sonic HedgeHog (Shh), recombinant human
| Catalog No: |
|
CRS600A
(datasheet)
|
| Brand: |
|
Cell Sciences |
| Quantity: |
|
5 µg |
| Price: |
|
$90.00
add to cart
|
|
|
| Category/Sub: |
|
Proteins and Peptides / Recombinant Proteins |
| Description: |
|
Members of the Hedgehog (Hh) family are highly conserved proteins which are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh) are structurally related and share a high degree of amino-acid sequence identity (e.g., Shh and Ihh are 93% identical). The biologically active form of Hh molecules is obtained by autocatalytic cleavage of their precursor proteins and corresponds to approximately the N-terminal one half of the precursor molecule. Although Hh proteins have unique expression patterns and distinct biological roles within their respective regions of secretion, they use the same signaling pathway and can substitute for each other in experimental systems. Recombinant Human Sonic HedgeHog is a 19.6 kDa protein consisting of 174 amino acid residues.
Source: E. coli
Format: Lyophilized
Purity: Greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
Biological Activity: The biological activity assay was determined by Measuring its ability to induce alkaline phosphatase production by C3H10T1/2 fibroblasts. The ED50 for this effect is typically 2 - 8 ug/ml.
|
|
|
|
|
|
Home | Products | New | Featured | Tech Questions | Announcements | Contact | Cart
|
|
Cell Sciences®
480 Neponset Street, Building 12A
Canton, MA 02021
Telephone: Toll Free 888-769-1246
Telephone: 781-828-0610 • Fax: 781-828-0542
info@cellsciences.com
Privacy Policy
|
|
All prices on this site are for orders shipping within the US and Canada. Prices are in US dollars.
These products are for laboratory research purposes only, not for any human or animal diagnostic or
therapeutic use.
All site content,
©
2002, 2003, 2004, 2005, 2006 Cell Sciences
All microscopic images,
©
1999, Dennis Kunkel
|
|
|
|
|
