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Mouse Anti-human Carcinoma Associated Antigen, Clone 115D8, Monoclonal
 
Catalog No:   HM2131     (datasheet)
Brand:   Hycult Biotech
Quantity:   100 µg
Price:   $420.00   add to cart

Category/Sub:   Monoclonal Antibodies / Adhesion Molecule Antibodies
Notes:   The antibody can be used for immunoprecipitation, Western blotting and immunohistology on frozen and paraffin sections.

The typical starting working dilution is 1:10.
Isotype:   Mouse IgG2b
Description:   Carcinoma associated antigen MAM-6, also known as a milk fat globule membrane antigen, is a mucus glycoprotein of >400 kD that is located mainly in the glycocalyx of most glandular epithelial cells. It is also located in the cytoplasm and on the membrane of most carcinoma cells and some other tumor cells.

Antibody 115D8 recognizes epitope “a” of MAM-6 and reacts very strongly with a majority of carcinomas (99.2%) and adenomas (61.4%). It occasionally shows a very weak cross reactivity with sarcomas and leukemias. It does not react with normal intestine or colorectal adenomas, but reacts with colorectal carcinomas.
Applications:   W, IH, IP


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