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Rabbit Anti-JNK1/SAPK pan, Polyclonal Antibody
 
Catalog No:   CPJ000     (datasheet)
Brand:   Cell Sciences
Quantity:   100 µg
Price:   $295.00   add to cart

Category/Sub:   Polyclonal Antibodies / Signal Transduction
Notes:   The antibody has been used in Western blotting and immunostaining applications.
Description:   c-Jun N-terminal Kinase 1 (JNK1) is a ~46 kDa Stress Activated Protein Kinase/Map Kinase (SAPK/MAPK) that is fully activated by dual phosphorylation on threonine 183 and tyrosine 185, within the activation loop. The JNK and p38 pathways function to modulate cell-cycle, apoptotic and transcriptional responses to stress. This antibody is useful to determine total levels of JNK1 protein.

Formulation: 0.50 mg/ml. Rabbit polyclonal immunoglobulin in phosphate buffer, pH 7.4, with 0.05% sodium azide.

Purification: Purified from rabbit serum by sequential epitope-specific chromatography.

Immunogen: The antiserum was produced against a chemically synthesized peptide derived from an internal region of JNK1. This region is conserved among human, mouse, and rat forms of JNK1, JNK2, and JNK3 proteins.

Cross-reactivity: Human, mouse, and rat JNK1.

Applications:   W, IS


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