Human Kininogen Total Antigen ELISA Kit

Synonyms:

BK; BDK; KNG

Species:

Human

Cat. No.:

CKH020A pdf (datasheet)

Quantity/Size:

1 x 96 tests

Price:

$450.00 BUY

Description:

This human high molecular weight Kininogen assay is intended for the quantitative determination of Kininogen in human plasma and serum. For research use only.

Kininogen (HK, aka Fitzgerald Factor) is the single chain 626 amino acid 120 kDa glycoprotein precursor of the vasoactive peptide bradykinin. Kininogen is an important cofactor for the activation of the zymogens prekallikrein, Factor XII, and Factor XI in the contact activation or intrinsic coagulation pathway. Additionally kininogen is a major inhibitor of systemic cysteine proteinases such cathepsins, calpain and papain.

Human Kininogen will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, horseradish peroxidase conjugated polyclonal anti-human Kininogen detection antibody binds to the captured protein. Following an additional washing step, TMB substrate is used for color development at 450 nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human Kininogen. The amount of color development is proportional to the concentration of total Kininogen in the sample.

Entrez Symbol:

KNG1

Data PDF:

CKH020

Kit Plates:

1 x 96 tests

Application:

ELISA