Mouse Anti-Human B7-2/CD86 Clone B-T7 FITC mAb

Molecule:

B7-2/CD86

Synonyms:

B-lymphocyte activation antigen, B7-2, B70, CD28LG2, LAB72

Species:

Human

Cat. No.:

CDM374 pdf (datasheet)

Quantity/Size:

100 tests

Price:

$390.00 BUY

Concentration:

100 tests/ml

Description:

The mouse monoclonal antibody recognizes human CD86, a immunoglobulin superfamily type I membrane protein expressed by antigen-presenting cells. CD86 the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4 (cytotoxic T-lymphocyte-associated protein 4). Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with CTLA-4 negatively regulates T-cell activation and diminishes the immune response.

Entrez Symbol:

CD86

Data PDF:

CDM374

Specificity:

Recognizes B7.2, B70 antigen, a 80 kDa protein.

Host Species:

Mouse

Immunogen:

B70 transfected P815 cell line.

Isotype:

IgG1

Clone:

B-T7

Conjugate:

FITC

Formulation:

Liquid in PBS + 1% BSA + 0.1% sodium azide.

Application notes:

Flow Cytometry: Use 10 µl to label 106 cells or 100 µl of whole blood.

Storage/Stability:

Stable at 2-8°C for 1 year. For longer storage, freeze aliquots at -20 to -80°C.