Mouse Anti-Human CD196 Clone B-R35 mAb

Synonyms:

BN-1, C-C CKR-6, CC-CKR-6, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22

Cat. No.:

CDM470 pdf (datasheet)

Quantity/Size:

200 tests

Price:

$275.00 BUY

Concentration:

100 tests/ml

Description:

The mouse monoclonal antibody recognizes human CCR6/CD196, a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR6 is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses.

Entrez Symbol:

CCR6

Data PDF:

CDM470

Specificity:

Human CD196/CCR6

Host Species:

Mouse

Immunogen:

Human CCR6-transfected NIH-3T3 cells

Isotype:

IgG2AK

Clone:

B-R35

Conjugate:

Unconjugated

Formulation:

Liquid in PBS+ 1% BSA + 0.09% sodium azide.

Application:

FC

Storage/Stability:

Stable at 2-8°C for 1 year. For long-term storage, freeze in aliquots at -20 to -80°C. Avoid repeated freeze-thaw cycles.