Mouse Anti-Human CD86 Clone B-T7 Azide Free mAb

Molecule:

B7-2/CD86

Synonyms:

CD86, B70, B7-2, B7.2, LAB72, CD28LG2

Species:

Human

Cat. No.:

CDM201 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$370.00 BUY

Concentration:

1 mg/ml

Description:

The mouse monoclonal antibody recognizes human CD86, an immunoglobulin superfamily type I membrane protein expressed by antigen-presenting cells. CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4 (cytotoxic T-lymphocyte-associated protein 4). Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with CTLA-4 negatively regulates T-cell activation and diminishes the immune response.

Entrez Symbol:

CD86

Uniprot Name:

T-lymphocyte activation antigen CD86

Uniprot ID:

P42081

Data PDF:

CDM201

Specificity:

Human | Recognizes B7.2, B70 antigen, a 80 kDa protein

Host Species:

Mouse

Immunogen:

B70 transfected P815 cell line

Isotype:

IgG1

Clone:

B-T7

Conjugate:

Unconjugated

Formulation:

Liquid in phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

FC

Application notes:

Inhibits Mixed Lymphocyte Culture

Storage/Stability:

Stable at +2-8°C for 12 months. For longer storage, freeze aliquots.