Mouse Anti-Human CXCR2 Clone 48311.211 mAb

Molecule:

IL-8RB/CXCR2

Synonyms:

CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB, C-X-C chemokine receptor type 2

Species:

Human

Cat. No.:

CMH049 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$595.00 BUY

Concentration:

0.5 mg/ml

Description:

The mouse monoclonal antibody recognizes human CXCR2, a member of the G-proteincoupled receptor family. CXCR2 is a receptor for interleukin 8 (IL-8). It binds to IL-8 with high affinity, and transduces the signal through a G-protein activated second messenger system. CXCR2 also binds to CXCL1/MGSA and has been shown to be a major component required for serum-dependent melanoma cell growth. CXCR2 mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL-8 in intestinal microvascular endothelial cells are found to be mediated by this receptor.

Entrez Symbol:

CXCR2

Data PDF:

CMH049

Specificity:

Human CXCR2

Host Species:

Mouse

Immunogen:

Human CXCR2 transfected NSO mouse myeloma cells

Isotype:

IgG2a

Clone:

48311.211

Conjugate:

Unconjugated

Formulation:

Liquid in PBS, pH 7.6 +15 mg/ml BSA + 0.01% thimerosal + 0.05% sodium azide.

Purification:

Protein G chromatography

Application:

Application notes:

FC: use 10 μg per 105 cells.
FS: Inhibition assays - recommended concentration 0.5 - 1.5 μg/ml.

Storage/Stability:

Store at 2-8°C for short term, or long term in working aliquots at -20°C. Avoid repeated freeze-thaw cycles .