Mouse Anti-Human E-Selectin/CD62E Azide free Clone B-P7 mAb

Molecule:

E-Selectin/CD62E

Synonyms:

ICAM-1; BB2; CD54; P3.58

Species:

Human

Cat. No.:

CDM049 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$390.00 BUY

Concentration:

1 mg/ml

Description:

Mouse Anti-Human E-Selectin/CD62E Clone B-P7 Azide Free mAb

This antibody can be used as a Capture Antibody in a human E-Selectin/CD62E sandwich Immunoassay to detect human E-Selectin/CD62E in combination with biotinylated human E-Selectin/CD62E Detection Antibody (Cat No CDM422).

Background: Selectin E, also known as CD62E, is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Entrez Symbol:

SELE

Uniprot Name:

E-selectin

Uniprot ID:

P16581

Data PDF:

CDM049

Specificity:

Human | Recognizes Endothelial Leucocyte Adhesion Molecule-1 (ELAM-1), E-selectin, a 97 kDa protein

Host Species:

Mouse

Immunogen:

Activated human endothelial cells

Isotype:

IgG1

Clone:

B-P7

Conjugate:

Unconjugated

Formulation:

Sterile filtered (through a 0.22 μm filter) liquid in PBS without preservative and carrier.

Purification:

Ion exchange Chromatography

Application:

ELISA

Application notes:

ELISA Capture Antibody: 2.5-5 µg/ml

Storage/Stability:

Antibody solution is stable at 2-4°C for 1 year. Aliquot and freeze for longer storage.