Mouse Anti-Human E-Selectin/CD62E Clone B-S3 Biotin Detection mAb

Molecule:

E-Selectin/CD62E

Synonyms:

ELAM; ESEL; CD62E; ELAM1; LECAM2

Species:

Human

Cat. No.:

CDM422 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$540.00 BUY

Concentration:

0.1 mg / 1.0 ml

Description:

Mouse Anti-Human E-Selectin/CD62E Clone B-S3 Biotin Detection mAb
This antibody can be used as a Detection Antibody in a human E-Selectin/CD62E sandwich immunoassay to detect human E-Selectin/CD62E in combination with human E-Selectin/CD62E Capture Antibody (Cat No CDM398 and CDM049).

Background: Selectin E, also known as CD62E, is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Entrez Symbol:

SELE

Data PDF:

CDM422

Specificity:

Recognizes Human Endothelial Leucocyte Adhesion Molecule-1 (ELAM-1), E-Selectin, a 97 kDa protein

Host Species:

Mouse

Immunogen:

Activated human endothelial cells

Isotype:

IgG1

Clone:

B-S3

Conjugate:

Biotin

Formulation:

Liquid in PBS with 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

ELISA Detection Antibody: 0.05-0.5 µg/ml

Storage/Stability:

Store at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.