The monoclonal antibody recognizes human CD130, also known as Interleukin 6 Signal Transducer or gp130.
This antibody can be used as a Capture Antibody in a human CD130/IL-6ST sandwich immunoassay in combination with biotinylated anti-human CD130/IL-6ST Detection Antibody (CDM420).
Background: IL-6ST is a signal transducer shared by many cytokines, including interleukin 6 (IL-6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). The protein functions as a part of the cytokine receptor complex and its activation is dependent upon the binding of cytokines to their receptors.
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