Mouse Anti-Human HtrA2 Clone 1B3 mAb

Synonyms:

OMI, PARK13, PRSS25, HtrA serine peptidase 2

Cat. No.:

CSI15563B pdf (datasheet)

Quantity/Size:

100 μl

Price:

$395.00 BUY

Concentration:

1 mg/ml

Description:

The mouse monoclonal antibody recognizes human HtrA2, a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP)-binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death.

Entrez Symbol:

HTRA2

Data PDF:

CSI15563

Specificity:

Human HtrA2/Omi

Host Species:

Mouse

Immunogen:

Recombinant human HtrA2/Omi (aa 134-458) purified from E. coli.

Isotype:

IgG1K

Clone:

1B3

Conjugate:

Unconjugated

Formulation:

Liquid in Phosphate-Buffered Saline (PBS), pH 7.4 + 10% glycerol + 0.02% sodium azide.

Purification:

Protein G Chromatography

Application:

ELISA

Application notes:

WB: Recommended dilution range 1:500 ~ 1:2,000.