Mouse Anti-Human IL-10 Clone B-S10 Azide Free Capture mAb

Molecule:

IL-10

Synonyms:

Interleukin 10, CSIF, TGIF, GVHDS, IL10A

Species:

Human

Cat. No.:

CDM404 pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$995.00 BUY

Concentration:

1.0 mg/ml

Description:

The monoclonal antibody recognizes human IL-10, a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway.

May be used as the capture antibody in a sandwich immunoassay to detect human IL-10. Recommended use in combination with biotinylated human IL-10 Detection Antibody (CDM428).

Entrez Symbol:

IL10

Data PDF:

CDM404

Specificity:

Recognizes both natural and recombinant human IL-10

Host Species:

Mouse

Immunogen:

Recombinant Human IL-10

Isotype:

IgG1

Clone:

B-S10

Conjugate:

Unconjugated

Formulation:

Liquid in PBS. Sterile filtered. Carrier and preservative free.

Application:

ELISA

Application notes:

Recommended coating concentrations:
ELISA: 1-5 μg/ml
ELISpot: 5-10 μg/ml

Storage/Stability:

Stable at 2-8°C for one year. For longer storage, freeze in working aliquots at -20 to -80° C.