Mouse Anti-Human IL-10 Clone B-S10 Azide Free mAb

Molecule:

IL-10

Synonyms:

IL10, IL-10, CSIF, TGIF, GVHDS, IL-10, IL10A

Species:

Human

Cat. No.:

CDM270 pdf (datasheet)

Quantity/Size:

500 μg

Price:

$540.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes human IL-10, a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway.

Entrez Symbol:

IL10

Uniprot Name:

Interleukin-10

Uniprot ID:

P22301

Data PDF:

CDM270

Specificity:

Human | Recognizes both natural and recombinant human IL-10

Host Species:

Mouse

Immunogen:

Recombinant human IL-10

Isotype:

IgG1

Clone:

B-S10

Conjugate:

Unconjugated

Formulation:

Liquid in phosphate-buffered saline. Sterile-filtered through 0.22 μm and treated to remove endotoxins. . Carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

BL

Application notes:

Blocks IL-10 induced proliferation on MC/9 cell line

Storage/Stability:

Stable at +2-8°C for 12 months. For longer storage, freeze aliquots.