Mouse Anti-Human IL-10 Clone B-T10 Azide Free mAb

Molecule:

IL-10

Synonyms:

IL-10, CSIF, GVHDS, IL-10A, TGIF, IL10

Species:

Human

Cat. No.:

CDM111 pdf (datasheet)

Quantity/Size:

500 μg

Price:

$540.00 BUY

Concentration:

1 mg/ml

Description:

Product: The monoclonal antibody recognizes human IL-10.

Background: IL-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes that has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

Entrez Symbol:

IL10

Uniprot Name:

Interleukin-10

Uniprot ID:

P22301

Data PDF:

CDM111

Specificity:

Human | Recognizes both natural and recombinant human IL-10

Host Species:

Mouse

Immunogen:

Recombinant human IL-10

Isotype:

IgG2b Kappa light chain

Clone:

B-T10

Conjugate:

Unconjugated

Formulation:

Liquid in phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Purification:

Ion exchange chromatography

Application:

ELISA

Storage/Stability:

Stable at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.