Mouse Anti-Human IL-13 Clone B-B13 Azide Free Capture mAb

Molecule:

IL-13

Synonyms:

P600; IL-13

Species:

Human

Cat. No.:

CDM407 pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$995.00 BUY

Concentration:

1.0 mg / 1.0 ml

Description:

Mouse Anti-Human IL-13 Clone B-B13 Azide Free Capture mAb

This antibody can be used as a Capture Antibody in a human IL-13 sandwich immunoassay to detect human IL-13 in combination with biotinylated human IL-13 Detection Antibody (Cat No CDM431).

Background: Interleukin 13 (IL-13) is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Entrez Symbol:

IL13

Data PDF:

CDM407

Host Species:

Mouse

Isotype:

IgG1

Conjugate:

Unconjugated

Formulation:

Liquid in PBS. Sterile-filtered through 0.22 µm. Carrier and Preservative free. Treated to remove endotoxins.

Application:

ELISA

Application notes:

Capture Antibody:
ELISA: 0.5-2.5 µg/ml
ELISPOT: 5-10 µg/ml

Storage/Stability:

Store at 2-4°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.