Mouse Anti-Human IL-13 Clone B-P6 Biotin Detection mAb

Molecule:

IL-13

Synonyms:

P600; IL-13

Species:

Human

Cat. No.:

CDM431 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$540.00 BUY

Concentration:

0.1 mg / 1.0 ml

Description:

Mouse Anti-Human IL-13 Clone B-P6 Biotin Detection mAb

This antibody can be used as a  Detection Antibody in a human IL-13 sandwich immunoassay to detect human IL-13 in combination with human IL-13 Capture Antibody (Cat No CDM407 and CDM275).

Background: Interleukin 13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Entrez Symbol:

IL13

Data PDF:

CDM431

Specificity:

Recognizes both natural and recombinant IL-13

Host Species:

Mouse

Immunogen:

Recombinant human IL-13

Isotype:

IgG1

Clone:

B-P6

Conjugate:

Biotin

Formulation:

Liquid in PBS with 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

Detection Antibody ELISA / ELISPOT: 0.05-0.5 µg/ml

Storage/Stability:

Store at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.