Mouse Anti-Human IL-17A Clone B-B51 Biotin Detection mAb

Molecule:

IL-17A

Species:

Human

Cat. No.:

CDM432 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$540.00 BUY

Concentration:

0.1 mg / 1.0 ml

Description:

Mouse Anti-Human IL-17A Clone B-B51 Biotin Detection monoclonal antibody for ELISA and ELISPOT.

This antibody can be used as the detection antibody in a human IL-17A sandwich immunoassay to detect Human IL-17A in combination with Human IL-17A Clone B-C49 Capture Antibody (Cat No CDM408 and CDM120).

Background: IL-17A is the original member of the IL-17 family of cytokines. IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages). IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells. High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Data PDF:

CDM432

Specificity:

Recognizes both Recombinant and Native Human IL-17A

Host Species:

Mouse

Immunogen:

Recombinant Human IL-17A

Isotype:

IgG2b

Clone:

B-B51

Conjugate:

Biotin

Formulation:

Liquid in PBS with 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

Detection Antibody: ELISA / ELISPOT: 0.05-0.5 µg/ml

Storage/Stability:

Stable for 1 year at 2-8°C or in working aliquots at -20°C for longer storage. Avoid repeated freeze-thaw cycles.