Mouse Anti-Human IL-17A Clone B-C49 Azide Free mAb

Molecule:

IL-17A

Synonyms:

IL17, CTLA8, IL-17, IL-17A

Species:

Human

Cat. No.:

CDM120 pdf (datasheet)

Quantity/Size:

500 μg

Price:

$540.00 BUY

Concentration:

1 mg/ml

Description:

Mouse Anti-Human IL-17A Clone B-C49 Monoclonal Antibody, Carrier and Preservative Free.

This antibody can be used as the capture antibody in a Human IL-17A sandwich Immunoassay to detect Human IL-17A in combination with Biotinylated Human IL-17A Clone B-B51 Detection Antibody (Cat No CDM432). 

Background: Interleukin-17 (IL-17, or IL-17A) is the original member of the IL-17 family of cytokines. IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages). IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells. High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Entrez Symbol:

IL17A

Uniprot Name:

Interleukin-17A

Uniprot ID:

Q16552

Data PDF:

CDM120

Specificity:

Human | Recognizes both recombinant and natural human IL-17A

Host Species:

Mouse

Immunogen:

Recombinant human IL-17A

Isotype:

IgG2b Kappa light chain

Clone:

B-C49

Conjugate:

Unconjugated

Formulation:

Liquid in phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

Capture Antibody:
ELISA: 1-5 µg/ml. ELISPOT: 5-10 µg/ml.

Storage/Stability:

Stable at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.