Mouse Anti-Human IL-17A Clone B-C49 Capture mAb

Molecule:

IL-17A

Synonyms:

IL17, CTLA8, IL-17, IL-17A

Species:

Human

Cat. No.:

CDM408 pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$995.00 BUY

Concentration:

1.0 mg / 1.0 ml

Description:

Mouse Anti-Human IL-17A Clone B-C49 Capture Monoclonal Antibody, Carrier and Preservative Free.

This antibody can be used as the capture antibody in a Human IL-17A sandwich immunoassay to detect Human IL-17A in combination with Biotinylated Human IL-17A Clone B-B51 Detection Antibody (Cat No CDM432).

Background: Interleukin-17 (IL-17, or IL-17A) is the original member of the IL-17 family of cytokines. IL-17A is involved in inducing and mediating proinflammatory responses, commonly associated with allergic responses and induces the production of many other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including IL-8, GRO-α and MCP-1) and prostaglandins (e.g. PGE2) from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages). IL-17A function is also essential to a subset of CD4+ T-Cells called T helper 17 (Th17) cells. High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Entrez Symbol:

IL17A

Data PDF:

CDM408

Specificity:

Recognizes both Recombinant and Native Human IL-17A

Host Species:

Mouse

Immunogen:

Recombinant Human IL-17A

Isotype:

IgG2b

Clone:

B-C49

Conjugate:

Unconjugated

Formulation:

PBS solution sterile filtered through a 0.22 µm filter. Carrier and preservative free.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

Capture Antibody
ELISA: 1-5 µg/ml
ELISPOT: 5-10 µg/ml.

Storage/Stability:

Stable for 1 year at 2-8°C or in working aliquots at -20°C for longer storage. Avoid repeated freeze-thaw cycles.