Mouse Anti-Human IL-17F Clone B-F60 Biotin Detection mAb

Molecule:

IL-17F

Synonyms:

ML1, ML-1, CANDF6, IL-17F

Species:

Human

Cat. No.:

CDM450 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$540.00 BUY

Concentration:

0.1 mg / ml

Description:

Mouse Anti-Human IL-17F Clone B-F60 Biotin Detection mAb

This antibody can be used as the detection antibody in a Human IL-17F sandwich Immunoassay to detect Human IL-17F in combination with Human IL-17F capture antibody Clone B-G46 (Cat No CDM416 and CDM123).

Background: IL-17F is a member of the IL-17 cytokine family produced by activated CD4+ T-cells and monocytes. IL-17F is considered an inflammatory cytokine since it induces many proinflammatory cytokines and chemokines. IL-17F shares strongest homology to IL-17A (sharing about 50% amino acid). The IL-17A and IL-17F genes are localized in the same chromosome region. An IL-17A/F biologically active heterodimer was found to be expressed in Th17 cells together with IL-17A and IL-17F homodimers. IL-17F stimulated the production of several other cytokines, including IL6, IL8, and GM-CSF. It also inhibits the angiogenesis of endothelial cells and induces endothelial cells to produce IL2, TGFB1, and MCP-1.

Entrez Symbol:

IL17F

Data PDF:

CDM450

Specificity:

Recognizes both Recombinant and Native Human IL-17F

Host Species:

Mouse

Immunogen:

Recombinant Human IL-17F

Isotype:

IgG2b

Clone:

B-F60

Conjugate:

Biotin

Formulation:

PBS with 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

Detection Antibody: ELISA / ELISPOT: 0.05-0.5 µg/ml

Storage/Stability:

Stable at 2-8°C for 12 months. For longer storage, freeze aliquots. Avoid repeated freeze-thaw cycles.