Mouse Anti-Human IL-23A Clone B-F43 Biotin Detection mAb

Molecule:

IL-23A

Synonyms:

P19; SGRF; IL-23; IL-23A; IL23P19

Species:

Human

Cat. No.:

CDM433 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$540.00 BUY

Concentration:

0.1 mg / 1.0 ml

Description:

Mouse Anti-Human IL-23A Clone B-F43 Biotin Detection mAb

This antibody can be used as a Detection Antibody in a human IL-23 sandwich immunoassay to detect human IL-23 in combination with human IL-23 Capture Antibody (Cat No CDM409 and CDM115).

Background: Interleukin 23A is a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.

Entrez Symbol:

IL23A

Data PDF:

CDM433

Specificity:

Recognizes both natural and recombinant IL-23, p19 sub-unit

Host Species:

Mouse

Immunogen:

Recombinant IL-23 (sub-unit p19)

Isotype:

IgG1

Clone:

B-F43

Conjugate:

Biotin

Formulation:

Liquid in PBS with 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

ELISA Detection Antibody: 0.05-0.5 µg/ml

Storage/Stability:

Store at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.