Mouse Anti-Human IL-23A Clone B-Z23 Azide Free mAb
This antibody can be used as a Capture Antibody in a human IL-23 sandwich immunoassay to detect human IL-23 in combination with biotinylated human IL-23 Detection Antibody (Cat No CDM433).
Background: Interleukin 23A is a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
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