Mouse Anti-Human IL-27 Clone B-G44 Azide Free Capture mAb

Molecule:

IL-27

Synonyms:

p28; IL30; IL-27; IL27A; IL-27A; IL27p28

Species:

Human

Cat. No.:

CDM410 pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$995.00 BUY

Concentration:

1.0 mg / 1.0 ml

Description:

Mouse Anti-Human IL-27 Clone B-G44 Azide Free Capture mAb

This antibody can be used as a Capture Antibody in a human IL-27 sandwich immunoassay to detect human IL-27 in combination with biotinylated human IL-27 Detection Antibody (Cat No CDM434).

Background: Interleukin 27 is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Entrez Symbol:

IL27

Data PDF:

CDM410

Specificity:

Recognizes both natural and recombinant human IL-27

Host Species:

Mouse

Immunogen:

Recombinant IL-27

Isotype:

IgG1

Clone:

B-G44

Conjugate:

Unconjugated

Formulation:

Liquid in phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

ELISA Capture Antibody: 0.5-2.5µg/ml

Storage/Stability:

Store at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.