Mouse Anti-Human IL-27 Clone B-G49 Biotin Detection mAb

Molecule:

IL-27

Synonyms:

p28; IL30; IL-27; IL27A; IL-27A; IL27p28

Species:

Human

Cat. No.:

CDM434 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$540.00 BUY

Concentration:

0.1 mg / 1.0 ml

Description:

Mouse Anti-Human IL-27 Clone B-G49 Biotin Detection mAb

This antibody can be used as a Detection Antibody in a human IL-27 sandwich immunoassay to detect human IL-27 in combination with human IL-27 Capture Antibody (Cat No CDM410 and CDM122).

Background: Interleukin 27 is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Entrez Symbol:

IL27

Data PDF:

CDM434

Purity:

Ion exchange chromatography

Specificity:

Recognizes both natural and recombinant IL-27

Host Species:

Mouse

Immunogen:

Recombinant IL-27

Isotype:

IgG2a

Clone:

B-G49

Conjugate:

Biotin

Formulation:

Liquid in PBS, with 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Application:

ELISA

Application notes:

ELISA Detection Antibody: 0.05 - 0.5 µg/ml

Storage/Stability:

Store at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.