Mouse Anti-Human IL-2R alpha Clone B-F2 Biotin Detection mAb

Molecule:

IL-2 R alpha

Synonyms:

p55; CD25; IL2R; IMD41; TCGFR; IDDM10

Species:

Human

Cat. No.:

CDM418 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$540.00 BUY

Concentration:

0.1 mg / 1.0 ml

Description:

Mouse Anti-Human IL-2R alpha Clone B-F2 Biotin Detection Monoclonal Antibody. This Antibody can be used as a Detection Antibody in a human IL2RA sandwich immunoassay to detect human IL2RA in combination with human IL2RA Capture Antibody (Cat No CDM394 and CDM005).

Background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Entrez Symbol:

IL2RA

Uniprot Name:

interleukin 2 receptor subunit alpha

Data PDF:

CDM418

Specificity:

Recognizes the Interleukin-2 Receptor alpha chain (IL-2Ra), a 55 kDa protein

Host Species:

Mouse

Immunogen:

PHA activated T cells

Isotype:

IgG1

Clone:

B-F2

Conjugate:

Biotin

Formulation:

Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

ELISA: 0.05-0.5 µg/ml

Storage/Stability:

Store at 2-4°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.