Mouse Anti-Human IL-2R alpha Clone B-G3 Azide Free Capture mAb

Molecule:

IL-2 R alpha

Synonyms:

p55; CD25; IL2R; IMD41; TCGFR; IDDM10

Species:

Human

Cat. No.:

CDM394 pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$995.00 BUY

Concentration:

1.0 mg / 1.0 ml

Description:

Mouse Anti-Human IL-2R alpha Clone B-G3 Azide Free Capture Monoclonal Antibody. ELISA Capture Antibody. This Antibody can be used as a Capture Antibody in a human IL2RA sandwich Immunoassay to detect human IL2RA in combination with biotinylated human IL2RA Detection Antibody (Cat No CDM418).
Background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Entrez Symbol:

IL2RA

Uniprot Name:

interleukin 2 receptor subunit alpha

Data PDF:

CDM394

Specificity:

Recognizes the Interleukin-2 Receptor alpha chain (IL-2Ra), a 55 kDa protein

Host Species:

Mouse

Immunogen:

PHA activated T cells

Isotype:

IgG1

Clone:

B-G3

Conjugate:

Unconjugated

Formulation:

Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and Preservative free

Application:

ELISA

Application notes:

ELISA Capture Antibody: 0.5-2.5 µg/ml

Storage/Stability:

Store at 2-4°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.