Mouse Anti-Human IL-4 Clone B-G28 Biotin Detection mAb

Molecule:

IL-4

Synonyms:

BSF1; IL-4; BCGF1; BSF-1; BCGF-1

Species:

Human

Cat. No.:

CDM425 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$540.00 BUY

Concentration:

0.1 mg / 1.0 ml

Description:

Mouse Anti-Human IL-4 Clone B-G28 Biotin Detection mAb

This antibody can be used as a Detection Antibody in a human IL-4 sandwich immunoassay to detect human IL-4 in combination with human IL-4 Capture Antibody (Cat No CDM401 and CDM104).

Background: Interleukin 4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Entrez Symbol:

IL4

Data PDF:

CDM425

Specificity:

Recognizes both natural and recombinant IL-4

Host Species:

Mouse

Immunogen:

Recombinant IL-4

Isotype:

IgG1

Clone:

B-G28

Conjugate:

Biotin

Formulation:

Phosphate-buffered saline. With 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

ELISA: 0.05-0.5 µg/ml

Storage/Stability:

Store at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.