Mouse Anti-Human IL-4 Clone B-R14 Azide Free mAb

Molecule:

IL-4

Synonyms:

BSF1; IL-4; BCGF1; BSF-1; BCGF-1

Species:

Human

Cat. No.:

CDM104 pdf (datasheet)

Quantity/Size:

500 μg

Price:

$540.00 BUY

Concentration:

1 mg/ml

Description:

Mouse Anti-Human IL-4 Clone B-R14 Azide Free mAb

This antibody can be used as Capture Antibody in a human IL-4 sandwich immunoassay to detect human IL-4 in combination with biotinylated human IL-4 Detection Antibody (Cat No CDM425).

Background: Interleukin 4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Entrez Symbol:

IL4

Uniprot Name:

Interleukin-4

Uniprot ID:

P05112

Data PDF:

CDM104

Specificity:

Human | Recognizes both natural and recombinant human IL-4

Host Species:

Mouse

Immunogen:

Recombinant human IL-4

Isotype:

IgG1 Kappa light chain

Clone:

B-R14

Conjugate:

Unconjugated

Formulation:

Liquid in phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

Capture Antibody:
ELISA: 0.05-0.5 µg/ml
ELISPOT: 5-10 µg/ml

Storage/Stability:

Stable at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.