Mouse Anti-Human IL-6R Azide free Clone B-N12 mAb

Molecule:

IL-6R

Synonyms:

IL6R, CD126, IL-6R-1, IL-6R-alpha, IL6RA, gp80

Species:

Human

Cat. No.:

CDM010 pdf (datasheet)

Quantity/Size:

200 μg

Price:

$355.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes human IL-6 receptor.

This antibody can be used as capture antibody in a human IL-6R sandwich immunoassay to detect human IL-6R in combination with biotinylated human IL-6R Detection Antibody (Cat No CDM419).

Background: IL-6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL-6 receptor is a protein complex consisting of this protein and IL-6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines.

Entrez Symbol:

IL6R

Uniprot Name:

Interleukin-6 receptor subunit alpha

Uniprot ID:

P08887

Data PDF:

CDM010

Specificity:

Human | Recognizes both soluble and membrane bound Interleukin-6 Receptor a subunit, IL-6 Ra, IL-6 R, a 80 kDa protein

Host Species:

Mouse

Immunogen:

gp80 transfected CHO cell line

Isotype:

IgG1

Clone:

B-N12

Conjugate:

Unconjugated

Formulation:

Sterile filtered (through a 0.22 μm filter) liquid in PBS without preservative and carrier.

Purification:

Ion exchange Chromatography

Application:

ELISA

Application notes:

No effect on IL-6 induced proliferation of XG-1 cell line

ELISA Capture Antibody: 0.3-1 µg/ml

Storage/Stability:

Antibody solution is stable at 2-4°C for 1 year. Aliquot and freeze for longer storage.