Mouse Anti-Human IL-7 Clone B-N18 Azide Free Capture mAb

Molecule:

IL-7

Synonyms:

IL-7

Species:

Human

Cat. No.:

CDM403 pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$995.00 BUY

Concentration:

1.0 mg / 1.0 ml

Description:

Mouse Anti-Human IL-7 Clone B-N18 Azide Free Capture mAb

This antibody can be used as a Capture Antibody in a human IL-7 sandwich Immunoassay to detect human IL-7 in combination with biotinylated human IL-7 Detection Antibody (Cat No CDM427).

Background: Interleukin 7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Entrez Symbol:

IL7

Data PDF:

CDM403

Specificity:

Recognizes both natural and recombinant IL-7

Host Species:

Mouse

Immunogen:

Recombinant human IL-7

Isotype:

IgG1

Clone:

B-N18

Conjugate:

Unconjugated

Formulation:

Liquid in PBS. Sterile-filtered through 0.22 µm. Carrier and Preservative free.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

ELISA: 0.5-2.5 µg/ml

Storage/Stability:

Store at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.