Mouse Anti-Human IL-7 Clone B-N18 Azide Free mAb

Molecule:

IL-7

Synonyms:

IL-7, IL7

Species:

Human

Cat. No.:

CDM097 pdf (datasheet)

Quantity/Size:

500 μg

Price:

$540.00 BUY

Concentration:

1 mg/ml

Description:

Mouse Anti-Human IL-7 Clone B-N18 Azide Free mAb

This antibody can be used as a Capture Antibody in a human IL-7 sandwich Immunoassay to detect human IL-7 in combination with biotinylated human IL-7 Detection Antibody (Cat No CDM427).

Background: Interleukin 7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Entrez Symbol:

IL7

Uniprot Name:

Interleukin-7

Uniprot ID:

P13232

Data PDF:

CDM097

Specificity:

Human | Recognizes both natural and recombinant human IL-7

Host Species:

Mouse

Immunogen:

Recombinant human IL-7

Isotype:

IgG1 kappa light chain

Clone:

B-N18

Conjugate:

Unconjugated

Formulation:

Liquid in phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

ELISA Capture Antibody: 0.5-2.5 µg/ml

Storage/Stability:

Stable at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.