Mouse Anti-Human IL-7 Clone B-S16 Biotin Detection mAb

Molecule:

IL-7

Synonyms:

IL-7, IL7

Species:

Human

Cat. No.:

CDM427 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$540.00 BUY

Concentration:

0.1 mg / 1.0 ml

Description:

Mouse Anti-Human IL-7 Clone B-S16 Biotin Detection mAb

This antibody can be used as Detection Antibody in a human IL-7 sandwich Immunoassay to detect human IL-7 in combination with human IL-7 Capture Antibody (Cat No CDM403 and CDM097).

Background: Interleukin 7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Entrez Symbol:

IL7

Data PDF:

CDM427

Specificity:

Recognizes both natural and recombinant IL-7

Host Species:

Mouse

Immunogen:

Recombinant IL-7

Isotype:

IgG1

Clone:

B-S16

Conjugate:

Biotin

Formulation:

Liquid in PBS with 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

ELISA Detection Antibody: 0.05-0.5 µg/ml

Storage/Stability:

Store at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.