Mouse Anti-Human Integrin beta 2/CD18 Clone MEM48 FITC mAb

Synonyms:

LAD; MF17; MFI7; LCAMB; LFA-1; MAC-1; CD18

Species:

Human

Cat. No.:

CDM444 pdf (datasheet)

Quantity/Size:

100 tests

Price:

$430.00 BUY

Description:

The monoclonal antibody recognizes human integrin beta 2/ CD18, an integrin beta chain that combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cellsurface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency.

Entrez Symbol:

ITGB2

Data PDF:

CDM444

Specificity:

Recognizes the human CD18 molecule, a 95 kDa integrin molecule (beta-2 integrin) that forms the common beta chain of the CD11/CD18 heterodimer integrins.

Host Species:

Mouse

Immunogen:

Leucocytes from an LGL-type leukemia

Isotype:

IgG1

Clone:

MEM48

Conjugate:

FITC

Formulation:

Liquid in PBS + 5% BSA + 0.1% sodium azide.

Application:

FC

Application notes:

Flow Cytometry: Use 10 µl to label 106 cells or 100 µl of whole blood.

Storage/Stability:

Stable for 1 year at 2-8°C. For longer storage, freeze in working aliquots at -20 to -80°C.