Mouse Anti-Human Integrin beta 2/CD18 Clone MEM48 mAb

Synonyms:

LAD; MF17; MFI7; LCAMB; LFA-1; MAC-1

Species:

Human

Cat. No.:

CDM446 pdf (datasheet)

Quantity/Size:

200 tests

Price:

$410.00 BUY

Concentration:

100 tests/ ml

Description:

The monoclonal antibody recognizes human integrin beta 2/ CD18, an integrin beta chain that combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency.

Entrez Symbol:

ITGB2

Data PDF:

CDM446

Specificity:

Recognizes the human CD18 molecule, a 95 kDa integrin molecule (beta-2 integrin) that forms the common beta chain of the CD11/CD18 heterodimer integrins.

Host Species:

Mouse

Immunogen:

Leucocytes from an LGL-type leukemia

Isotype:

IgG1

Clone:

MEM48

Formulation:

Liquid in PBS + 1% BSA + 0.09% sodium azide.

Application:

Storage/Stability:

Stable for 1 year at 2-8°C. For longer storage, freeze in working aliquots at -20 to -80°C. Avoid repeated freeze-thaw cycles.