Mouse Anti-Human Integrin beta 2/CD18 Clone MEM48 mAb Azide Free

Synonyms:

LAD; MF17; MFI7; LCAMB; LFA-1; MAC-1; CD18

Species:

Human

Cat. No.:

CDM443 pdf (datasheet)

Quantity/Size:

200 µg

Price:

$410.00 BUY

Concentration:

1 mg/ml

Description:

The monoclonal antibody recognizes human integrin beta 2/ CD18, an integrin beta chain that combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cellsurface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency.

Entrez Symbol:

ITGB2

Data PDF:

CDM443

Specificity:

Recognizes the human CD18 molecule, a 95 kDa integrin molecule (beta-2 integrin) that forms the common beta chain of the CD11/CD18 heterodimer integrins.

Host Species:

Mouse

Immunogen:

Leucocytes from an LGL-type leukemia

Isotype:

IgG1

Clone:

MEM48

Conjugate:

Unconjugated

Formulation:

Liquid in PBS. Sterile-filtered and treated to remove endotoxins. Carrier and preservative free.

Application:

Application notes:

Flow Cytometry, Immunohistochemistry, Functional Studies
Tested for identification of CD18+ leucocytes present on cryostat sections.

Storage/Stability:

Stable for 1 year at 2-8°C. For longer storage, freeze in working aliquots at -20 to -80°C.