Mouse Anti-Human Integrin beta 2/CD18 Clone MEM48 PE mAb

Synonyms:

LAD; MF17; MFI7; LCAMB; LFA-1; MAC-1; CD18

Species:

Human

Cat. No.:

CDM445 pdf (datasheet)

Quantity/Size:

100 tests

Price:

$500.00 BUY

Description:

The monoclonal antibody recognizes human integrin beta 2/ CD18, an integrin beta chain that combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency.

Entrez Symbol:

ITGB2

Data PDF:

CDM445

Specificity:

Recognizes the human CD18 molecule, a 95 kDa integrin molecule (beta-2 integrin) that forms the common beta chain of the CD11/CD18 heterodimer integrins.

Host Species:

Mouse

Immunogen:

Leucocytes from an LGL-type leukemia

Isotype:

IgG1

Clone:

MEM48

Conjugate:

PE

Formulation:

Lyophilized from PBS + 5% BSA + 0.1% sodium azide.

Reconstitution:

Reconstitute with 1 ml deionized water

Application:

FC

Application notes:

Flow Cytometry: Use 10 µl to label 106 cells or 100 µl of whole blood.

Storage/Stability:

Reconstituted antibody is stable for 6 months at 2-8°C. DO NOT FREEZE.