Mouse Anti-Human Integrin beta 3/CD61 Clone CRC54 mAb

Molecule:

ITGB3 | CD61

Synonyms:

GT, CD61 , GP3A , BDPLT2 , GPIIIa , BDPLT16

Species:

Human

Cat. No.:

MON1147 pdf (datasheet)

Quantity/Size:

1 ml

Price:

$475.00 BUY

Description:

CRC54 monoclonal antibody reacts with the platelet glycoprotein gpIIIa/VNR beta chain. This glycoprotein is the common beta chain (Integrin beta 3) of the cytoadhesins, gpIIbIIIa and VNR. The antibody reacts with platelets and megakaryocytes. The antibody reacts preferentially with the activated/occupied form of platelet GPIIb-IIIa (ligand-induced biding site or LIBS epitope) and dissociated form of GPIIIa. CRC54-epitope is located within the N-terminal region of GPIIIa (first 100 amino acids). CRC54 does not react with platelets of patients with Glanzmann thrombastenia.

Entrez Symbol:

ITGB3

Data PDF:

MON1147

Specificity:

Human Integrin beta 3/CD61

Host Species:

Mouse

Isotype:

IgG1?

Clone:

CRC54

Formulation:

Lyophilized in PBS with approximately 0.2 mg antibody/ml + 0.09% sodium azide. Sodium Azide.

Purification:

Ammonium Sulfate + DEAE-cellulose gradient elution

Reconstitution:

Centrifuge vial prior to opening. Reconstitute with 1 ml sterile distilled water. Sufficient for 100 tests.

Application notes:

MON1147 can be used for: -Determination of thrombocytes in blood. -Identification of megakaryocytes and -blasts in tissue. -Immunoblotting under reduced and non-reduced conditions. -Detection of conformational changes of GPIIb-IIIa on activated platel

Storage/Stability:

Store antibody at 2-8οΨΑC.