Mouse Anti-Human Melanoma-associated antigen Clone NKI/beteb mAb

Molecule:

MAA

Synonyms:

CT1.1 , MAGE1

Species:

Human

Cat. No.:

MON7006-1 pdf (datasheet)

Quantity/Size:

1 ml

Price:

$360.00 BUY

Concentration:

100 οΨΒg/ml

Description:

Melanoma associated antigen (MAA) is dispersed in the cytoplasma of melanoma cells, and is more concentrated inside vacuoles and sometimes on the melanosomes. Occasionally the antigen is seen on the cell surface. The antigen is actively shed from living cells. Although the antigen is associated with melanomas, it is not codistributed with the tyrosinase activity associated with melagonesis. The antigen shows codistribution with cathepsin D, which is a marker for lysosomal functions. The antibody NKI/beteb recognizes a (pre)melanosomal 100 kD and 7 kD antigen (glycoprotein). The antibody reacts with melanomas, clear cells sarcomas (melanoma of soft tissue), nevocellular nevi, and normal melanocytes. Except for one case of non-Hodgkin's lymphoma in which macrophages were positive, no reactions with other tumors or tissues have been observed.

Entrez Symbol:

MAGEA1

Data PDF:

MON7006

Specificity:

The antibody can be used for immunofluorescence and immunohistology on frozen and paraffin sections (formalin fixation and embedding in paraffin may affect the reactivity of the antibody). Dilutions to be used depend on detection system applied. It is rec

Host Species:

Mouse

Isotype:

IgG2b

Clone:

NKI/beteb

Formulation:

1 ml of a 0.2 οΨΒm filtered antibody solution in PBS + 0.02% sodium azide + 0.1% BSA.

Application notes:

The antibody can be used for immunofluorescence and immunohistology on frozen and paraffin sections (formalin fixation and embedding in paraffin may affect the reactivity of the antibody). Dilutions to be used depend on detection system applied. It is rec

Storage/Stability:

Product should be stored at 4οΨΑC. Under recommended storage conditions, product is stable for one year.