Mouse Anti-Human Perforin Clone B-D48 Biotin Detection mAb

Molecule:

PRF1

Synonyms:

P1; PFP; FLH2; PFN1; HPLH2

Species:

Human

Cat. No.:

CDM438 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$540.00 BUY

Concentration:

0.1 mg / 1.0 ml

Description:

Mouse Anti-Human Perforin Clone B-D48 Biotin Detection mAb

This antibody can be used as a Detection Antibody in a human Perforin sandwich Immunoassay to detect human Perforin in combination with  human Perforin Capture Antibody (Cat No CDM414 and CDM090).

Background: Perforin 1 has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood.

Entrez Symbol:

PRF1

Data PDF:

CDM438

Specificity:

Recognizes human perforin, a 70 kDa protein

Host Species:

Mouse

Immunogen:

Natural human perforin

Isotype:

IgG1

Clone:

B-D48

Conjugate:

Biotin

Formulation:

Liquid in PBS with 1% BSA and 0.09% Sodium Azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.

Application:

ELISA

Application notes:

Detection Antibody ELISA / ELISPOT: 0.05-0.5 µg/ml

Storage/Stability:

Store at 2-4°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.