Mouse Anti-Human Perforin Clone B-E48 Azide Free Capture mAb

Molecule:

PRF1

Synonyms:

P1; PFP; FLH2; PFN1; HPLH2

Species:

Human

Cat. No.:

CDM414 pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$995.00 BUY

Concentration:

1.0 mg / 1.0 ml

Description:

Mouse Anti-Human Perforin Clone B-E48 Azide Free Capture mAb

This antibody can be used as a Capture Antibody in a human Perforin sandwich immunoassay to detect human Perforin in combination with biotinylated human Perforin Detection Antibody (Cat No CDM438).

Background: Perforin 1 has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood.

Entrez Symbol:

PRF1

Data PDF:

CDM414

Specificity:

Recognizes human perforin, a 70 kDa protein

Host Species:

Mouse

Immunogen:

Natural human perforin

Isotype:

IgG2b

Clone:

B-E48

Conjugate:

Unconjugated

Formulation:

Liquid in PBS. Sterile-filtered through 0.22 µm. Carrier and Preservative free.

Application:

ELISA

Application notes:

Capture Antibody
ELISA: 0.5-2.5 µg/ml
ELISPOT: 5-10 µg/ml

Storage/Stability:

Store at 2-8°C for 12 months. For longer storage, freeze aliquots at -20°C. Avoid repeated freeze-thaw cycles.