Mouse Anti-Human TGF-beta 2 mAb

Molecule:

TGF-beta 2

Synonyms:

LDS4 , TGF-beta2

Cat. No.:

MAB1 pdf (datasheet)

Quantity/Size:

0.5 mg

Price:

$295.00 BUY

Description:

The monoclonal antibody recognizes human TGF-beta 2, a member of the transforming growth factor beta (TGF beta) family of cytokines. TGF beta cytokines are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFbR1 and TGFbR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers.

For Western Blot use a working dilution of 1:1,000.
For Immunohistochemistry use a working dilution of 1:10-1:50.
The optimal concentration should be determined by the user for each specific application.

Does not inhibit the binding of TGF-β2 to the type 2 TGF-β receptor in mink lung epithelial cells (Mv1Lu) and is not a neutralizing antibody.

Entrez Symbol:

TGFB2

Data PDF:

MAB1

Specificity:

Human TGF-beta 2

Host Species:

Mouse

Immunogen:

Synthetic peptide corresponding to amino acids 50-75 of human TGF-β2

Isotype:

IgG1

Conjugate:

Unconjugated

Formulation:

Lyophilized

Purification:

Purified from conditioned medium by Protein G agarose chromatography

Reconstitution:

Dissolve in 1 ml sterile water and dilute in a buffer suitable for the desired application.

Application notes:

Western blot: working dilution of 1:1,000. Immunohistochemistry: working dilution of 1:10-1:50.

Storage/Stability:

Stable for 2 years at 2-8°C. After reconstitution, store in working aliquots at -20°C to -80°C. Avoid repeated freeze-thaw cycles.