Mouse Anti-Human TNF-alpha Clone B-C7 Biotin Detection mAb

Molecule:

TNF-alpha

Synonyms:

DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha

Species:

Human

Cat. No.:

CDM436 pdf (datasheet)

Quantity/Size:

100 μg

Price:

$540.00 BUY

Concentration:

0.1 mg/ml

Description:

Mouse Anti-Human TNF-alpha Clone B-C7 Biotin Detection mAb

This antibody can be used as a detection antibody in a human TNF-alpha sandwich immunoassay to detect human TNF-alpha in combination with human TNF-alpha capture antibody (Cat no. CDM412 and CDM287).

Background: Tumor Necrosis Factor alpha (TNF-alpha) is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Entrez Symbol:

TNF

Uniprot Name:

Tumor necrosis factor

Uniprot ID:

P01375

Data PDF:

CDM436

Specificity:

Human | Recognizes both natural and recombinant TNF-alpha

Host Species:

Mouse

Immunogen:

Recombinant human TNF-alpha

Isotype:

IgG1

Clone:

B-C7

Conjugate:

Biotin

Formulation:

Liquid in phosphate-buffered saline with 1% BSA and 0.09% Sodium Azide.

Purification:

Ion exchange chromatography

Application:

ELISA

Application notes:

Detection Antibody, ELISA, ELISPOT: 0.05-0.5 µg/ml

Storage/Stability:

Store at +2-8°C for 12 months.