Mouse Anti-Human TNFR1 Clone MR1-2 mAb

Synonyms:

CD120a, FPF, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60

Species:

Human

Cat. No.:

MON9062 pdf (datasheet)

Quantity/Size:

1 ml

Price:

$640.00 BUY

Concentration:

100 μg/ml

Description:

The mouse monoclonal antibody recognizes human Tumor Necrosis Factor Receptor 1 (TNFR1), a member of the TNF receptor superfamily of proteins. TNFR1 is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, TNF-alpha. Binding of membrane-bound TNF-alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free TNF-alpha to inhibit inflammation.

Entrez Symbol:

TNFRSF1A

Data PDF:

MON9062

Host Species:

Mouse

Isotype:

IgG1

Formulation:

Liquid in sterile-filtered PBS + 0.1% BSA + 0.02% sodium azide

Application:

Application notes:

IHC: Frozen sections. Recommended positive controls for frozen sections - human lymph nodes. FC: Recommended positive control - PHA activated T cells.

Storage/Stability:

Product is stable at 2-8°C for up to 1 year.