Mouse Anti-Human TNFR2 Clone 80M2 mAb

Synonyms:

p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II

Cat. No.:

MON9059 pdf (datasheet)

Quantity/Size:

100 μg

Price:

$1,035.00 BUY

Concentration:

100 μg/ml

Description:

The antibody reacts with the extra-cellular part of the TNF-RII. It also reacts with the soluble receptor. TNF-RII is present on most cell types and is considered to be an important co-stimulator together with TNF-RI in cellular responses to TNF-alpha, in particular the transmembrane form of TNF-alpha. A dominant role of TNF-RII has been shown in thymocyte activation by TNF-alpha.

The antibody is a non-agonistic receptor modulating antibody. It enhances in vitro TNF responses by increasing the affinity of the soluble form to TNF-alpha to TNF-RII. The antibody is useful for flow cytometry and immunohistology on frozen sections.
Furthermore the antibody is useful for immuno precipitation, Western blotting and immuno assays. The reactivity of the antibody with cellbound TNF-Receptor is minimally inhibited by high concentrations of TNF-alpha.

Entrez Symbol:

TNFRSF1B

Data PDF:

MON9059

Host Species:

Mouse

Isotype:

IgG

Formulation:

1 ml (100 μg/ml) 0.2 μm filtered antibody solution in PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin

Application:

Application notes:

For immunohistology, flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Storage/Stability:

Product should be stored at 2-4°C. Under recommended storage conditions, product is stable for one year.