Mouse Anti-Human Trypsin Clone 7C8 mAb

Molecule:

TRY

Synonyms:

TRP1 , TRY1 , TRY4 , TRYP1

Species:

Human

Cat. No.:

CSI17396C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$4,995.00 BUY

Concentration:

1 mg/ml

Description:

Trypsin is a 24 kDa enzyme and is a member of the serine proteinase family produced in the pancreas as an inactive precursor trypsinogen. The active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin predominantly cleaves proteins at the carboxyl side of the amino acids lysine and arginine. A common trypsin substrate is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screen for and diagnose Cystic Fibrosis.

Entrez Symbol:

PRSS1

Data PDF:

CSI17396

Specificity:

Specific for Human Trypsin, Trypsinogen and Trypsin in complex with alpha-1-Antitrypsin (A1AT).

Host Species:

Mouse

Immunogen:

Trypsin purified from Human pancreatic tissue and adsorbed onto aluminum hydroxide gel

Isotype:

IgG1?

Clone:

7C8

Formulation:

Liquid in 0.01 M Phosphate buffer pH 7.4 + 0.5 M NaCl + 15 mM Sodium Azide. Precaution: Sodium Azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purification:

Protein A purified

Application notes:

Reacts with Human Trypsin coated directly onto a microtiter plate and can be used as both a capture and detection antibody in sandwich ELISA. Recognizes Human Trypsin in Western blotting under reducing conditions. The optimal concentration should be deter

Storage/Stability:

Store in the dark at 4-8οΨΑC. Product is light sensitive.