Mouse Anti-Human VEGF 165 Clone B-G55 Azide Free mAb

Molecule:

VEGFA

Synonyms:

VPF; VEGF; MVCD1

Species:

Human

Cat. No.:

CDM477 pdf (datasheet)

Quantity/Size:

500 μg

Price:

$540.00 BUY

Description:

This antibody recognizes both native and recombinant human VEGF 165 / VEGFA.

Background: Vascular endothelial growth factor A (VEGFA) is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis.

Entrez Symbol:

VEGFA

Data PDF:

CDM477

Specificity:

Recognizes both native and recombinant human VEGF 165

Host Species:

Mouse

Immunogen:

Recombinant human VEGF 165

Isotype:

IgG2BK

Clone:

B-G55

Conjugate:

Unconjugated

Formulation:

Liquid in PBS. Sterile-filtered. Carrier and preservative-free.

Application:

ELISA

Storage/Stability:

Stable at 2-8°C for 1 year. For long-term, freeze in aliquots at -20 to -80°C. Avoid repeated freeze-thaw cycles.