Native Human alpha-Fetoprotein

Molecule:

alpha-Fetoprotein/AFP

Synonyms:

FETA, HPAFP, OTTHUMP00000160480, alpha-1-fetoprotein, alpha-fetoglobulin,alpha-fetoprotein , alpha-fetoglobulin , alpha-1-fetoprotein

Species:

Human

Cat. No.:

CSI10379 pdf (datasheet)

Quantity/Size:

100 μg

Price:

$250.00 BUY

Description:

Background: Human Alpha Fetoprotein (AFP) is a protein that is normally only produced in the fetus during its development. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Concentration:

Typically >1mg/ml

Entrez Symbol:

AFP

Uniprot Name:

Alpha-fetoprotein

Uniprot ID:

P02771

Data PDF:

CSI10379

Source:

Human Cord blood

Molecular Weight:

69 kDa

Physical State:

Liquid

Formulation:

0.2 µm sterile filtered liquid in tris buffered saline, pH 7.5 + 0.1% Sodium Azide. Precaution: Sodium Azide is a poisonous and hazardous substance which should be handled by trained staff only.

Purity:

>95% by SDS PAGE analysis.

Storage/Stability:

Stable for 2 years at 2-4°C. DO NOT FREEZE.