Native Human Platelet Factor 4

Molecule:

Platelet Factor 4

Synonyms:

CXCL4, C-X-C motif chemokine 4, SCYB4

Species:

Human

Cat. No.:

CRP271B pdf (datasheet)

Quantity/Size:

0.5 mg

Price:

$1,330.00 BUY

Description:

Product: Human PF-4 is prepared from the supernatant of thrombin-activated platelets by heparin-agarose affinity chromatography. Purity is assessed by SDS-PAGE analysis and heparin-neutralizing activity is verified by clotting assay.

Background: Platelet Factor 4 (PF4) is a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum.

Concentration:

≥ 1.5 mg/ml

Entrez Symbol:

PF4

Uniprot Name:

Platelet factor 4

Uniprot ID:

P02776

Data PDF:

CRP271

Source:

Human plasma

Molecular Weight:

29 kDa

Physical State:

Frozen liquid

Formulation:

Sterile filtered liquid (Frozen) in 0.025 M HEPES, pH 7.4 + 2.0 M NaCl.

Purity:

>95% by SDS-PAGE analysis.

Biological Activity:

~100 U/mg (1 unit will neutralize 1 IU of heparin in 1 ml of normal plasma.) Heparin-neutralizing activity is verified by clotting assay.

Storage/Stability:

Frozen liquid protein is stable at -80℃ for 3 years from date of delivery.