Native Human Cystatin C

Molecule:

Cystatin C

Synonyms:

CST3, Cystatin 3, Gamma Trace

Species:

Human

Cat. No.:

CSI19648B pdf (datasheet)

Quantity/Size:

1 mg

Price:

$970.00 BUY

Description:

Human Cystatin C is a small cysteine proteinase inhibitor of mol wt. 13 kDa present in all human body fluids. Human Cystatin C is a serum protein that is filtered out of the blood by the kidneys. Human Cystatin C serves as a measure of kidney function. Human Cystatin C is produced steadily by all types of nucleated cells in the body. Human Cystain C low molecular mass allows it to be freely filtered by the glomerular membrane in the kidney. Human Cystatin C concentration in blood correlates with the glomerular filtration rate.

Cystatin C is a marker for allograph function in adult transplant patients. It regulates extracellular cysteine protease activity, which results from microbial invasion or release of lysosomal proteinases from dying or diseased cells. It is freely filtered by the glomerular basement membrane (GBM) and serum concentration has been shown to correlate well with glomerular filtration rate (GFR).

Concentration:

1.0-3.0 mg/ml

Entrez Symbol:

CST3

Uniprot Name:

cystatin C

Uniprot ID:

P01034

Data PDF:

CSI19648

Source:

Human urine

Formulation:

Frozen Liquid

Purity:

≥ 95% (SDS-PAGE)

Storage/Stability:

Store at -20°C. Avoid repeated freeze-thaw cycles.